Dysregulation of the <scp>MEK</scp>/<scp>ERK</scp>/<scp>MNK</scp>1 signalling cascade by middle T antigen of the trichoydsplasia spinulosa polyomavirus

Abstract

Given that PP2A interaction and MEK/ERK/MNK1 phosphorylation are associated with high levels of cell proliferation and inflammation, our findings provide new evidence that TSPyV mT antigen may contribute to the pro-proliferative conditions that lead to TS development.