Pitfalls in genetic testing: a case of a <scp>SNP</scp> in primer‐annealing region leading to allele dropout in <i><scp>BRCA</scp>1</i>

Abstract

Assuming that this problem can also occur in any PCR-based method that are widely used in diagnostic settings, the clinical report presented here draws attention for one of the limitations of genetic testing in general, for which medical and laboratory communities need to be aware.