OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA–NF-κB pathway - Concepedia

Concepedia

Publication | Open Access

OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA–NF-κB pathway

DOI Full Paper Access

91

Citations

31

References

2017

Year

Mohamed Jalloul Nsaibia, Marie‐Chloé Boulanger, Rihab Bouchareb, Ghada Mkannez, Khaï Le Quang, Fayez Hadji, Déborah Argaud, Abdellaziz Dahou, Yohan Bossé, Marlys L. Koschinsky,

Cardiovascular Research

Abstract

OxLDL-LPA promotes an osteogenic program in the aortic valve through a LPAR1-RhoA/ROCK-p65 pS536 pathway. LPAR1 may represent a suitable target to prevent the progression of CAVS.

References

	Year	Citations

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