Animal nutrition · 2017 · 41 citations · 25 references
Life SciencesImmunologyNutritional SciencesInflammationNutritional ImmunologySwine MedicineFeed CompositionNutritional Modulation Of CytokinesSpleen PhysiologySplenic PathologySwine ImmunologySwine NutritionNutritional ImmunomodulationNutritional Modulation Of InflammationNutritional Regulation Of Interleukin-6Pro-inflammatory ChemokinesPro-inflammatory Cytokine CascadesPro-inflammatory Mediator ProductionSplenic FunctionZearalenone Exposure
) was observed as dietary ZEA increased. Swelling splenocyte in 1.1 mg/kg ZEA treatments, atrophy of white pulp and swelling of red pulp in 2.0 and 3.2 mg/kg ZEA treatments were observed. The cytoplasmic edema in 1.1 mg/kg ZEA treatments, significant chromatin deformation in 2.0 mg/kg ZEA treatment and phagocytosis in 3.2 mg/kg ZEA treatment were observed. Results suggested that dietary ZEA at 1.1 to 3.2 mg/kg can induce splenic damages and negatively affect immune function of spleen in post-weanling gilts.
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Effects of mycotoxins on human immune functions in vitro
L Berek, I Petri, Ákos Mesterházy et al. · Toxicology in Vitro · 2001 · 185 citations