Biomedical Optics Express · 2017 · 14 citations · 25 references
Health ProfessionsBiomedical EngineeringOphthalmologyBiomedical OpticsOcular ImagingVisual OpticsOphthalmic ImagingRetinal ExaminationRetinal ImagingScanning Laser OphthalmoscopyAnatomical RepresentationHigh-contrast MaterialsIn Vivo Retinal ImagingScan DesignSignal-to-noise RatioSignal-to-noise Ratio AnalysisSignal-to-noise Ratio EnhancementSignal-to-noise Ratio Improvement
Retinal imaging is demonstrated using a novel scanning light ophthalmoscope based on a digital micromirror device with 810 nm illumination. Concentric circles were used as scan patterns, which facilitated fixation by a human subject for imaging. An annular illumination was implemented in the system to reduce the background caused by corneal reflections and thereby to enhance the signal-to-noise ratio. A 1.9-fold increase in the signal-to-noise ratio was found by using an annular illumination aperture compared to a circular illumination aperture, resulting in a 5-fold increase in imaging speed and a better signal-to-noise ratio compared to our previous system. We tested the imaging performance of our system by performing non-mydriatic imaging on two subjects at a speed of 7 Hz with a maximum 20° (diameter) field of view. The images were shot noise limited and clearly show various anatomical features of the retina with high contrast.
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Confocal scanning laser ophthalmoscope
Robert H. Webb, George W. Hughes, François C. Delori · Applied Optics · 1987 · 596 citations
Spectral reflectance of the human ocular fundus
François C. Delori, Kent P. Pflibsen · Applied Optics · 1989 · 380 citations
Robert H. Webb, George W. Hughes, Oleg Pomerantzeff · Applied Optics · 1980 · 267 citations