Effects of an <scp>EP2</scp> and <scp>EP3</scp> Receptor Dual Agonist, <scp>ONO</scp>‐8055, on a Radical Hysterectomy‐Induced Underactive Bladder Model in Monkeys

Abstract

We developed a neurogenic UAB model in primates. As ONO-8055 improved voiding function in this model to at least the same degree as DIS, this EP2 and EP3 receptor dual agonist has the potential to be a candidate for neurogenic UAB pharmacotherapy.