Deep convolutional neural network based HEp-2 cell classification

Abstract

As different staining patterns of HEp-2 cells indicate different diseases, the classification of Indirect Immune Fluorescence (IIF) images on Human Epithelial-2 (HEp-2) cell is important for clinical applications. Different from traditional pattern recognition techniques, we use CNN to extract more high-level features for cell images classification. Compared to the existing CNN based HEp-2 classification methods, we proposed a network with deeper architecture. A class-balanced approach is also proposed to augment the HEp-2 cell dataset for network training. The proposed framework achieves an average class accuracy of 79.29% on ICPR 2012 HEp-2 dataset and a mean class accuracy of 98.26% on ICPR 2016 HEp-2 training set.