Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

Levi A. Garraway, Hans R. Widlund, Mark A. Rubin et al. · Nature · 2005 · 1.5K citations

Radiation Oncology, Oncology, Medicine +10

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.

Timothy J. Hemesath, Gaël McGill, Michael J. Hansen et al. · Genes & Development · 1994 · 668 citations · Full text

Critical Factor, Genetics, Genomic Mechanism +19

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

Corine Bertolotto, Fabienne Lesueur, Sandy Giuliano et al. · Nature · 2011 · 513 citations

Somatic Variant, Genetics, Melanoma +7

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

Satoru Yokoyama, Susan L. Woods, Glen M. Boyle et al. · Nature · 2011 · 466 citations · Full text

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition

Cory M. Johannessen, Laura A. Johnson, Federica Piccioni et al. · Nature · 2013 · 450 citations · Full text