The potentiating effect of <scp>hTFPI</scp> in the presence of <scp>hCD</scp>47 reduces the cytotoxicity of human macrophages

Abstract

When hCD47 was expressed, the expression of hTFPI leaded to tyrosine phosphorylation of SIRP-α in activated THP-1 cells via hTSP-1 inhibition, and consequently, it might improve the effect of hCD47-SIRP-a signaling.