A comparative study of tissue-engineered constructs from <i>Acropora</i> and <i>Porites</i> coral in a large animal bone defect model

Abstract

Bone regeneration in critical-size defects could be obtained with full bioresorption of the scaffold using coral-based TECs in a large animal model. The superior performance of <i>Acropora</i>-TECs brings us closer to a clinical application, probably because of more suitable bioresorption kinetics. However, nonunion still occurred in nearly half of the bone defects.<b>Cite this article:</b> A. Decambron, M. Manassero, M. Bensidhoum, B. Lecuelle, D. Logeart-Avramoglou, H. Petite, V. Viateau. A comparative study of tissue-engineered constructs from <i>Acropora</i> and <i>Porites</i> coral in a large animal bone defect model. <i>Bone Joint Res</i> 2017;6:208-215. DOI: 10.1302/2046-3758.64.BJR-2016-0236.R1.