Concepedia

TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase

Kaizhe Wang, Ling Ye, Hongfang Lü, Huili Chen, Yanyan Zhang, Yunlong Huang, Jialin Zheng

Journal of Neuroinflammation · 2017 · 87 citations · 39 references

DOIFull text

Open access

Abstract

These findings suggest that glutaminase is an important metabolic factor controlling EV release from astrocytes during neuroinflammation.

References

39

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Elisabetta Polazzi, Ilaria Mengoni, Marco Caprini et al. · Neurosignals · 2012 · 9K citations · Full text

Glutamate neurotoxicity and diseases of the nervous system

Dennis W. Choi · Neuron · 1988 · 8K citations

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Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids

Clotilde Théry, Sebastián Amigorena, Graça Raposo et al. · Current Protocols in Cell Biology · 2006 · 5.7K citations

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Identification and proteomic profiling of exosomes in human urine

Trairak Pisitkun, Rong‐Fong Shen, Mark A. Knepper · Proceedings of the National Academy of Sciences · 2004 · 2.1K citations · Full text

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

Lin Zhang, Siyuan Zhang, Jun Yao et al. · Nature · 2015 · 1.1K citations · Full text

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