Novel benzothiazole based imidazole derivatives as new cytotoxic agents against glioma (C6) and liver (hepG2) cancer cell lines

Abstract

Cancer is the second leading cause of death after heart disease throughout the world. A great amount of anticancer drugs are discovered and still have been designed nowadays for cancer treatment 1 . Today, treatments involving cytotoxic drugs are used in a widespread manner because of increasing in cancer incidence 2 . Compounds containing imidazole and benzothiazole moiety have shown a wide range of biological properties including anticancer, antiviral, antitubercular, antimicrobial, antidiabetic, anti-inflammatory activities. These broad thera-