Concepedia

Metal-free chloroamidation of indoles with sulfonamides and NaClO

Xiaodong Liu, Kun Tong, Ai Hua Zhang, Ren Xiang Tan, Shouyun Yu

Organic Chemistry Frontiers · 2017 · 23 citations · 29 references

DOI

Concepts

Abstract

An efficient and rapid protocol for chloroamidation of indoles with sulfonamides and aqueous NaClO has been developed. The reaction completes in less than half an hour at room temperature without any transition metals.

References

29

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