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<i>Cystathionine γ-Lyase</i> Deficiency Exacerbates CCl <sub>4</sub> -Induced Acute Hepatitis and Fibrosis in the Mouse Liver

DOI

33

Citations

26

References

2016

Year

Lei Ci, Xingyu Yang, Xiaowen Gu, Qing Li, Yang Guo, Ziping Zhou, Jiahao Shi, Hua Yang, Zhugang Wang, Jian Fei
Antioxidants and Redox Signaling

Abstract

CSE deficiency increases pro-inflammatory cytokines in the liver and exacerbates acute hepatitis and liver fibrosis by reducing H<sub>2</sub>S production from L-cysteine in the liver. The present data suggest the potential of an H<sub>2</sub>S donor for the treatment of liver diseases such as toxic hepatitis and fibrosis. Antioxid. Redox Signal. 27, 133-149.

References

YearCitations

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