Concepedia

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease

Romain Bouziat, Reinhard Hinterleitner, Judy J. Brown, Jennifer Stencel-Baerenwald, Mine R. Ikizler, Toufic Mayassi, Marlies Meisel, Sangman M. Kim, Valentina Discepolo, Andrea J. Pruijssers,

Science · 2017 · 453 citations · 54 references

DOIFull text

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Concepts

Abstract

conversion, which was mediated by type-1 interferon. Last, our study in humans supports a role for infection with reovirus, a seemingly innocuous virus, in triggering the development of CeD.

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