Half-sandwich iridium N-heterocyclic carbene anticancer complexes

Chuanlan Wang, Jinfeng Liu, Zhenzhen Tian, Meng Tian, Laijin Tian, Wenqian Zhao, Zhe Liu

Dalton Transactions · 2017 · 103 citations · 60 references

Concepts

Abstract

concentrations of the complexes, and increase the amount of reactive oxygen species (ROS) dramatically, which appears to contribute to the anticancer activity. This class of organometallic Ir complexes has unusual features worthy of further exploration in the design of novel anticancer drugs.

References

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