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β‐Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α‐PP2A‐Mediated Dephosphorylation

DOIFull Paper Access

40

Citations

43

References

2017

Year

Kate L. Weeks, Antonella Ranieri, Agnieszka Karaś, Bianca C. Bernardo, Alexandra S. Ashcroft, Chris Molenaar, Julie R. McMullen, Metin Avkiran
Journal of the American Heart Association

Abstract

β-AR stimulation induces HDAC5 nuclear accumulation in cardiomyocytes by a mechanism that is protein kinase A-dependent but requires B55α-PP2A-mediated dephosphorylation of Ser259/Ser498 rather than protein kinase A-mediated phosphorylation of Ser279.

References

YearCitations

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