Concepedia

HDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells

Francesco Marampon, Francesca Megiorni, Simona Camero, Clara Crescioli, Heather P. McDowell, Roberta Sferra, Antonella Vetuschi, Simona Pompili, Luca Ventura, Francesca De Felice,

Cancer Letters · 2017 · 104 citations · 30 references

DOI

Concepts

References

30

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Roger Stupp, Monika E. Hegi, Warren Mason et al. · The Lancet Oncology · 2009 · 7.8K citations

, , +17

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

, , +16

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

V. G. Allfrey, Robert Faulkner, A. E. Mirsky · Proceedings of the National Academy of Sciences · 1964 · 2.6K citations · Full text

, , +10

Gamma-H2AX - a novel biomarker for DNA double-strand breaks.

Linda J Kuo, Li‐Xi Yang · PubMed · 2008 · 1.2K citations

, , +17

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

Takao Kanzawa, Isabelle M. Germano, Tadashi Komata et al. · Cell Death and Differentiation · 2004 · 984 citations

, , +11