Biomarker Profiles in Heart Failure Patients With Preserved and Reduced Ejection Fraction

Abstract

In HFpEF, inflammation and angiogenesis-mediated interactions are predominantly observed, while stretch-mediated interactions are found in HFrEF. The remodeling marker osteopontin and the angiogenesis marker neuropilin predicted outcome in HFpEF, but not in HFrEF.