Developmental Psychobiology · 2017 · 27 citations · 68 references
Social SciencesGeneticsPsychologyBehavioral GeneticsChild DevelopmentDevelopmental PsychologyChild PsychopathologyDevelopmental Behavioral GeneticsFamily StressParentingDifferential SusceptibilityEarly-life StressMaternal ParentingMaternal Stress EffectsParent-child Genetic InterplaySerotonin Transporter Gene VariantsSerotonin Transporter PolymorphismSleep Problems In Children
Abstract This study examined three potential moderators of the relations between maternal parenting stress and preschoolers’ adjustment problems: a genetic polymorphism—the short allele of the serotonin transporter (5‐HTTLPR, ss / sl allele) gene, a physiological indicator—children's baseline respiratory sinus arrhythmia (RSA), and a behavioral indicator—mothers’ reports of children's negative emotionality. A total of 108 mothers ( M age = 30.68 years, SD age = 6.06) reported on their parenting stress as well as their preschoolers’ ( M age = 3.50 years, SD age = 0.51, 61% boys) negative emotionality and internalizing, externalizing, and sleep problems. Results indicated that the genetic sensitivity variable functioned according to a differential susceptibility model; however, the results involving physiological and behavioral sensitivity factors were most consistent with a diathesis‐stress framework. Implications for prevention and intervention efforts to counter the effects of parenting stress are discussed.
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Multiple regression: testing and interpreting interactions
Choice Reviews Online · 1992 · 37.2K citations
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
Avshalom Caspi, Karen Sugden, Terrie E. Moffitt et al. · Science · 2003 · 8.1K citations