Concepedia

C-2 (E)-4-(Styryl)aniline substituted diphenylpyrimidine derivatives (Sty-DPPYs) as specific kinase inhibitors targeting clinical resistance related EGFRT790M mutant

Anran Song, Jianbin Zhang, Ge Yang, Changyuan Wang, Qiang Meng, Zeyao Tang, Jinyong Peng, Kexin Liu, Yanxia Li, Xiaodong Ma

Bioorganic & Medicinal Chemistry · 2017 · 14 citations · 21 references

Open access

Concepts

MedicineOncologyPharmacologyCancer PharmacologyMolecular OncologyMolecular PharmacologyTyrosine Kinase InhibitorsEgfr InhibitionKinase Inhibitor ResistanceKinase InhibitorsKinase Mutation-mediated ResistanceProtein Kinase InhibitorsResistance To Tyrosine Kinase InhibitorsSmall Molecule Tyrosine Kinase InhibitorsTherapeutic Tyrosine Kinase Inhibitors

References

21

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

Garrett M. Morris, Ruth Huey, William Lindstrom et al. · Journal of Computational Chemistry · 2009 · 25K citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +13

Cancer statistics, 2013

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2013 · 11.9K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Cancer Statistics, 2009

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2009 · 9.7K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

<i>EGFR</i> Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

Susumu Kobayashi, Titus J. Boggon, Tajhal Dayaram et al. · New England Journal of Medicine · 2005 · 3.9K citations · Full text

Medicine, Oncology, Pharmacology +15

Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers

Hisayuki Shigematsu, Tsuyoshi Takahashi, Masatoshi Nomura et al. · JNCI Journal of the National Cancer Institute · 2005 · 2.4K citations

Medicine, Genetics, Oncology +17