Influence of <i> <scp>ABCC</scp> 2, <scp>CYP</scp> 2C8 </i> , and <i> <scp>CYP</scp> 2J2 </i> Polymorphisms on Tacrolimus and Mycophenolate Sodium–Based Treatment in Brazilian Kidney Transplant Recipients - Concepedia

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Influence of <i> <scp>ABCC</scp> 2, <scp>CYP</scp> 2C8 </i> , and <i> <scp>CYP</scp> 2J2 </i> Polymorphisms on Tacrolimus and Mycophenolate Sodium–Based Treatment in Brazilian Kidney Transplant Recipients

36

Citations

22

References

2017

Year

Fabiana Dalla Vecchia Genvigir, Álvaro Mitsunori Nishikawa, Cláudia Rosso Felipe, Hélio Tedesco‐Silva, N. Oliveira, Antony Brayan Campos Salazar, José Medina‐Pestana, Sonia Q. Doi, Mário Hiroyuki Hirata, Rosário Dominguez Crespo Hirata

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Abstract

The ABCC2 c.3972C >T polymorphism affected tacrolimus C:D in Brazilian kidney transplant recipients. Further, CYP2C8*3 and CYP2J2 c.-76G>T SNPs influenced the renal function of these patients and the occurrence of adverse events during treatment with tacrolimus and mycophenolate sodium.

References

	Year	Citations

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