In vitro apoptosis-inducing effect and gene expression profiles of mixed ligand Cu(<scp>ii</scp>) complexes derived from 4-acyl pyrazolones on human lung cancer cells

Abstract

Mixed-ligand Cu(<sc>ii</sc>) complexes of 4-acylpyrazolone ligands and poly pyridyls were synthesized, characterized and their anticancer activity was evaluated against A549 lung carcinoma cell lines.