BODIPY-containing nanoscale metal–organic frameworks as contrast agents for computed tomography

Tao Zhang, Lei Wang, Chong Ma, Weiqi Wang, Jun Ding, Shi Liu, Xuewen Zhang, Zhigang Xie

Journal of Materials Chemistry B · 2017 · 91 citations · 56 references

Concepts

Abstract

). In vivo CT imaging results indicate that the as-synthesized UiO-PDT nanocrystals can preferentially accumulate in the tumor sites, not in the surrounding connective tissues and organs for rats bearing hepatomas, and give the best imaging performance after intravenous administration for about 24 h. The aforementioned findings suggest that such nanocrystals may have potential for use as CT contrast agents.

References

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