Plasmin Cleaves Von Willebrand Factor at K1491-R1492 in the A1–A2 Linker Region in a Shear- and Glycan-Dependent Manner In Vitro - Concepedia

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Plasmin Cleaves Von Willebrand Factor at K1491-R1492 in the A1–A2 Linker Region in a Shear- and Glycan-Dependent Manner In Vitro

DOI Full Paper Access

38

Citations

57

References

2017

Year

Teresa M. Brophy, Soracha E. Ward, Thomas R. McGimsey, Sonja Schneppenheim, Clive Drakeford, Jamie M. O’Sullivan, Alain Chion, Ulrich Budde, James S. O’Donnell

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Improved understanding of the plasmin-VWF interaction offers exciting opportunities to develop novel adjunctive therapies for the treatment of refractory thrombotic thrombocytopenic purpura.

References

	Year	Citations

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