Science Translational Medicine · 2017 · 228 citations · 44 references
Life SciencesImmunologyMicrobiologyInflammationMicrobiome ResearchMucosal ImmunologyGastrointestinal ImmunologyGastrointestinal InflammationGastrointestinal PathophysiologyGut MicrobiomeGut MicrobiotaMucosal InflammationGut Microbiota EffectsImmune Modulation By Gut MicrobesInflammatory Bowel Disease PathogenesisIntestinal Microbiota EffectsIntestinal Mucosal ImmunityMicrobiota-host PhysiologyPurine Catabolism
in mice. In addition, we found a positive correlation between elevated uric acid and anti-yeast antibodies in human sera. Thus, yeast in the gut may be able to potentiate metabolite production that negatively affects the course of inflammatory bowel disease.
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