Apolipoprotein E mimetic peptide, <scp>CN</scp>‐105, improves outcomes in ischemic stroke

Abstract

CN-105 improves functional and histological outcomes in a murine model of ischemic stroke via modulation of neuroinflammatory pathways. Recent clinical trial of this compound has demonstrated favorable pharmacokinetic and safety profile, suggesting that CN-105 represents an attractive candidate for clinical translation.