Concepedia

PPAR-γ promotes type 2 immune responses in allergy and nematode infection

Ting Chen, Christopher A. Tibbitt, Xiaogang Feng, Julian M. Stark, Leona Rohrbeck, Lisa Rausch, Saikiran K. Sedimbi, Mikael C. I. Karlsson, Bart N. Lambrecht, Gunilla B. Karlsson Hedestam,

Science Immunology · 2017 · 117 citations · 34 references

DOI

Concepts

Abstract

2 cells. These results pinpoint PPAR-γ as a factor that drives type 2 responses in allergy, worm infection, and visceral adipose tissue.

References

34

IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

Jochen Schmitz, Alexander M. Owyang, Elizabeth R. Oldham et al. · Immunity · 2005 · 3.7K citations · Full text

, , +13

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.4K citations · Full text

, , +17

Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

Justin I. Odegaard, Roberto R. Ricardo-González, Matthew H. Goforth et al. · Nature · 2007 · 2.1K citations · Full text

, , +15

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

Miriam F. Moffatt, Florence Démenais, David P. Strachan et al. · New England Journal of Medicine · 2010 · 2K citations · Full text

, , +13

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson et al. · Cell · 1995 · 2K citations · Full text

, , +16