On the impact of smoothing and noise on robustness of <scp>CT</scp> and <scp>CBCT</scp> radiomics features for patients with head and neck cancers

Abstract

Radiomics features extracted from planning CT and daily CBCT image datasets for head/neck cancer patients were robust to low-power Gaussian noise and low-pass filtering, but were impacted by high-pass filtering. Textural features extracted from CBCT and pCT image datasets were similar, suggesting interchangeability of pCT and CBCT for investigating radiomics features as possible biomarkers for outcome.