A facile water-stable MOF-based “off–on” fluorescent switch for label-free detection of dopamine in biological fluid

Yue Cheng, Jie Wu, Chao Guo, Xinge Li, Yan Li

Journal of Materials Chemistry B · 2017 · 67 citations · 78 references

Concepts

Abstract

-MOF and the reduced iodine ions. Therefore, the fluorescence signal can be gradually turned "on". The relative intensity of restored fluorescence is proportional to the concentration of DA in the wide linear range of 0.25-50 μM with a low detection limit of 57 nM (S/N = 3). Additionally, some potentially foreign interfering substances, such as ascorbic acid (AA) and uric acid (UA), glucide, amino acids and metal ions did not affect DA determination significantly. The proposed strategy was also successfully applied for DA determination in biological samples with satisfactory recoveries from 94.5% to 102%.

References

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