Still equivalent for dose calculation in the Monte Carlo era? A comparison of free breathing and average intensity projection <scp>CT</scp> datasets for lung <scp>SBRT</scp> using three generations of dose calculation algorithms

Abstract

With the capability to more accurately model inhomogeneity, Monte Carlo (Type-C) algorithms are sensitive to respiration-induced local and global tissue density changes and exhibit a strong correlation between dosimetric and density differences. However, FB and AIP CTs may still be considered equivalent for dose calculation in the Monte Carlo era, due to the small magnitude of lung density differences between these two datasets.