Ex vivo Akt inhibition promotes the generation of potent CD19CAR T cells for adoptive immunotherapy - Concepedia

Concepedia

Publication | Open Access

Ex vivo Akt inhibition promotes the generation of potent CD19CAR T cells for adoptive immunotherapy

DOI Full Paper Access

95

Citations

32

References

2017

Year

Ryan Urak, Miriam Walter, Laura Lim, ChingLam W. Wong, Lihua E. Budde, Sandra H. Thomas, Stephen J. Forman, Xiuli Wang

Journal for ImmunoTherapy of Cancer

Abstract

Inhibition of Akt signaling during ex vivo priming and expansion gives rise to CD19CAR T cell populations that display comparatively higher antitumor activity.

References

	Year	Citations

Page 1