Human papillomavirus/p16 positive head and neck cancer in India: Prevalence, clinical impact, and influence of tobacco use - Concepedia

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Human papillomavirus/p16 positive head and neck cancer in India: Prevalence, clinical impact, and influence of tobacco use

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References

2016

Year

Vedang Murthy, Monali Swain, Tanuja Teni, Shashi Singh Pawar, Prajakta Kalkar, Asawari Patil, Ajit Chande, Sujata Ghonge, S. Ghosh Laskar, Tejpal Gupta,

Indian Journal of Cancer

Abstract

The low prevalence of p16 positivity (20%) and dual HPV and p16 positivity (38.8%) in the studied Indian cohort indicates the low utility of p16 as a surrogate for HPV in the background of high tobacco burden. The outcomes are largely improved in a small subset of SCCHN cases comprising p16 +ve tobacco nonusers.