Metal‐Free Oxidative Decarboxylative Acylation/Ring Expansion of Vinylcyclobutanols with <i>α</i>‐Keto Acids by Visible Light Photoredox Catalysis

Abstract

Abstract A metal‐free visible‐light‐mediated decarboxylative acylation/ring expansion of vinylcyclobutanols with α ‐keto acids has been developed. Hypervalent iodine reagent was found to be important for promoting decarboxylation of α ‐keto acids in this tandem radical process. This protocol has been successfully applied to synthesis of a variety of substituted 1,4‐dicarbonyl compounds and tolerated some functional groups well.