Concepedia

Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives

Gao-Xiang Zhu, Pi-Le Cheng, Masuo Goto, Na Zhang, Susan L. Morris‐Natschke, Kan‐Yen Hsieh, Guan‐Zhou Yang, Qian-Ru Yang, Ying-Qian Liu, Hai-Le Chen,

Bioorganic & Medicinal Chemistry Letters · 2017 · 24 citations · 22 references

DOI

Concepts

References

22

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

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The mechanism of topoisomerase I poisoning by a camptothecin analog

Bart L. Staker, Kathryn A. Hjerrild, M.D. Feese et al. · Proceedings of the National Academy of Sciences · 2002 · 802 citations · Full text

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Molecular Modeling Studies of the DNA−Topoisomerase I Ternary Cleavable Complex with Camptothecin

Yi Fan, John N. Weinstein, Kurt W. Kohn et al. · Journal of Medicinal Chemistry · 1998 · 173 citations

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The Novel Silatecan 7-<i>tert</i>-Butyldimethylsilyl-10-hydroxycamptothecin Displays High Lipophilicity, Improved Human Blood Stability, and Potent Anticancer Activity

David Bom, Dennis P. Curran, Stefan Kruszewski et al. · Journal of Medicinal Chemistry · 2000 · 155 citations

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Novel 7-Oxyiminomethyl Derivatives of Camptothecin with Potent in Vitro and in Vivo Antitumor Activity

Sabrina Dallavalle, Anna Maria Ferrari, Barbara Biasotti et al. · Journal of Medicinal Chemistry · 2001 · 103 citations

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