Discovery of <i>MYH14</i> as an important and unique deafness gene causing prelingually severe autosomal dominant nonsyndromic hearing loss

Abstract

In the present study, we report that MYH14 can manifest as nonsyndromic prelingual severe sensorineural hearing loss in an AD fashion in Koreans. The results of the present study suggest that further genetic studies of similar patients should consider MYH14 as a causative gene, and cochlear implantation during infant or early childhood should be indicated for those patients with certain MYH14 pathogenic variants.