Gold-Catalyzed Cycloisomerization/1,5-H Migration/Diels–Alder Reaction Cascade: Synthesis of Complex Nitrogen-Containing Heterocycles

Abstract

An unprecedented gold-catalyzed cycloisomerization/1,5-H migration/Diels-Alder reaction cascade has been developed that enables the rapid construction of complex nitrogen polycyclic compounds. This one-pot, three-step cascade reaction offers good yields of the products and is promoted by a single gold catalyst under very mild conditions.