Concepedia

Gallic acid attenuates hypertension, cardiac remodeling, and fibrosis in mice with N G-nitro-L-arginine methyl ester-induced hypertension via regulation of histone deacetylase 1 or histone deacetylase 2

Jin Li, Ming Quan Lin, Zhe Piao, Jae Yeong Cho, Gwi Ran Kim, Sin Young Choi, Yuhee Ryu, Simei Sun, Hae Jin Kee, Myung Ho Jeong

Journal of Hypertension · 2017 · 68 citations · 30 references

DOI

Abstract

These results suggested that gallic acid may be a potential therapeutic agent for the treatment of cardiovascular diseases with hypertension and cardiac fibrosis.

References

30

Myocardial Fibrosis and Stiffness With Hypertrophy and Heart Failure in the Spontaneously Hypertensive Rat

Chester H. Conrad, Wesley W. Brooks, John A. Hayes et al. · Circulation · 1995 · 444 citations

Inhibition of Histone Deacetylation Blocks Cardiac Hypertrophy Induced by Angiotensin II Infusion and Aortic Banding

Hae Jin Kee, Il Suk Sohn, Kwang Il Nam et al. · Circulation · 2005 · 363 citations · Full text

Histone Deacetylation Inhibition in Pulmonary Hypertension

Lan Zhao, Chien-Nien Chen, Nabil Hajji et al. · Circulation · 2012 · 257 citations · Full text

Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-β1-induced renal injury

Hyunjin Noh, Eun Young Oh, Ji Yeon Seo et al. · American Journal of Physiology-Renal Physiology · 2009 · 249 citations

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Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition

Weichao Guo, Bin Shan, Ross C. Klingsberg et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2009 · 215 citations · Full text

, , +15