Bacillus Calmette-Guérin Confers Neuroprotection in a Murine Model of Japanese Encephalitis

Abstract

These findings indicate that the administration of BCG offers neuroprotection in the murine model of JE. BCG should therefore be further investigated as an adjuvant in the management of JE. BCG is an accepted vaccine for tuberculosis in many countries that are endemic for JEV. This approach may have a significant impact on the public health burden in these countries.