The majority of patients with metastatic melanoma are not represented in pivotal phase III immunotherapy trials

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

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PD-1 blockade induces responses by inhibiting adaptive immune resistance

Paul C. Tumeh, Christina L. Harview, Jennifer H. Yearley et al. · Nature · 2014 · 6.6K citations · Full text

Life Sciences, Immunology, Pathology +14

Pembrolizumab versus Ipilimumab in Advanced Melanoma

Caroline Robert, Jacob Schachter, Georgina V. Long et al. · New England Journal of Medicine · 2015 · 5.8K citations · Full text

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Nivolumab in Previously Untreated Melanoma without <i>BRAF</i> Mutation

Caroline Robert, Georgina V. Long, Benjamin Brady et al. · New England Journal of Medicine · 2014 · 5.4K citations · Full text

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