PubMed · 1970 · 54 citations · 6 references
Life SciencesDevelopmental BiologyImmunologyDevelopmental ImmunologyFetal PhysiologyImmune MaturationImmune OntogenyPregnancy ImmunologyPrenatal DevelopmentThymic DevelopmentFetal Immune PhysiologyGestation PeriodGestation PhysiologyImmune Response In PregnancyMaternal-fetal Immune DevelopmentMaternal-fetal ImmunologyThymic Differentiation
Human foetal thymocytes first respond to phytohaemagglutinin at about 14 weeks gestation. This corresponds to the completion of thymic differentiation and is perhaps the earliest, but still indirect, evidence of immune competence in the foetus.
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