Value of CNRIP1 promoter methylation in colorectal cancer screening and prognosis assessment and its influence on the activity of cancer cells

Abstract

The methylation status at locus 2245 within the CNRIP1 promoter region has potential value for the early detection and prognostic evaluation of colorectal cancers. Demethylation of the <i>CNRIP1</i> promoter or overexpression of <i>CNRIP1</i> can reduce the proliferative and migration abilities of colon cancer cells.