Prognostic significance of vascular endothelial growth factor polymorphisms in colorectal cancer patients

Abstract

AIM: ) -1498C>T and -634G>C, with the survival of patients with colorectal cancer (CRC). METHODS: -634G>C polymorphism in 118 patients. The analysis of association between categorical variables was performed using logistic regression, survival by Kaplan-Meier method and multivariate analysis by the Cox regression method. RESULTS: -634C>G acted as an independent prognostic factor for the risk of death in CRC patients. CONCLUSION: -634C>G polymorphisms are prognostic factors of survival in Brazilians patients with sporadic colorectal carcinoma.