Concepedia

Protective role of p53 in acetaminophen hepatotoxicity

Yazhen Huo, Shutao Yin, Mingzhu Yan, Sanda Win, Tin Aung Than, Mariam Aghajan, Hongbo Hu, Neil Kaplowitz

Free Radical Biology and Medicine · 2017 · 46 citations · 14 references

DOI

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References

14

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

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Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Hideaki Kamata, Shinichi Honda, Shin Maeda et al. · Cell · 2005 · 1.8K citations · Full text

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A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

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LIVER NECROSIS FROM PARACETAMOL

Eldon M. Boyd, G. M. BERECZKY · British Journal of Pharmacology and Chemotherapy · 1966 · 297 citations · Full text

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c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity

Chieko Saito, John J. Lemasters, Hartmut Jaeschke · Toxicology and Applied Pharmacology · 2010 · 270 citations

, , +15