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Novel dual-reverse thermosensitive solid lipid nanoparticle-loaded hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial burst effect

Improved BioavailabilityNanomedicineBiopolymer GelEngineeringPolymer-drug ConjugateRectal AdministrationNano-drug DeliveryBiomedical EngineeringDrug Delivery SystemPharmacology