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Functional Upregulation of STIM-1/Orai-1-Mediated Store-Operated Ca2+ Contributing to the Hypertension Development Elicited by Chronic EtOH Consumption

DOI

22

Citations

0

References

2017

Year

Guilherme Henrique Souza Bomfim, Iago Méndez‐López, Juan Alberto Arranz‐Tagarro, Adriana Aparecida Ferraz Carbonel, Danilo Roman‐Campos, Juan Fernando Padín, Aron Jurkiewicz, Neide Hyppolito Jurkiewicz
Current Vascular Pharmacology

Abstract

These findings suggest that hypertrophic aortic remodeling and abnormal contraction triggered mainly by Ca2+ overload via STIM-1/Orai-1-mediated SOCE through SOCCs are involved hypertension developed by EtOH consumption.