Activation of endoplasmic reticulum calcium leak by 2-APB depends on the luminal calcium concentration

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

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Bh3-only Protein Bim, Apoptosis, Cell Death +4

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.

Jonathan Lytton, Marisa M. Westlin, Michael R. Hanley · Journal of Biological Chemistry · 1991 · 1.3K citations · Full text

Cytoskeleton, Cellular Physiology, Molecular Pharmacology +19

2APB, 2-Aminoethoxydiphenyl Borate, a Membrane-Penetrable Modulator of Ins(1,4,5)P3-Induced Ca2+ Release

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Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

Haruo Takemura, Arlene R. Hughes, Ole Thastrup et al. · Journal of Biological Chemistry · 1989 · 886 citations · Full text

Calcium Entry, Tumor Promoter Thapsigargin, Parotid Acinar Cells +17