Synthesis, characterization, and antimicrobial activity of two Schiff base silver(I) complexes derived from 4-carboxybenzaldehyde

Abstract

Two new Schiff base silver(I) complexes, {[Ag(L1)][H2O]}∞ (1) and {[Ag(L2)][H2O]}∞ (2), where L1 = 4-((2-diethylaminoethylimino)methyl)phenecarboxylate and L2 = 4-([3-(morpholin-4-yl)propyl]iminomethyl)phenecarboxylate, have been synthesized and characterized. X-ray crystallographic analysis reveals that silver ions in 1 are bridged by L1 to form a one-dimensional zigzag chain, while three silver ions in 2 are linked by L2 to produce a two-dimensional coordination polymer. Guest water molecules in 1 generate a one-dimensional hydrogen-bonded chain. Both 1 and 2 offer high antibacterial activity against Gram-positive bacteria Staphylococcus aureus with MIC values of 0.26 and 0.24 mM and to exhibit good inhibitory activity against urease with the respective IC50 values of 3.5 ± 0.1 and 3.8 ± 0.2 μM.