Electrophilic Trifluoromethyl‐ and Fluoroalkylselenolation of Organometallic Reagents

Abstract

Fluoroalkylseleno groups are emerging groups that still suffer from a lack of efficient methods for introduction onto organic molecules. Herein, we describe an efficient method to perform reactions between in situ formed fluoroalkaneselenyl chlorides and organometallic reagents. With this strategy, various fluoroalkylselenolated molecules were easily obtained. Furthermore, the Hansch parameter of the CF 3 Se group was determined for the first time.