Concepedia

Occurrence of <i>bla</i> <sub>KPC-2</sub> , <i>bla</i> <sub>CTX-M</sub> , and <i>mcr-1</i> in Enterobacteriaceae from Well Water in Rural China

Pan Sun, Zhenwang Bi, Maud Nilsson, Beiwen Zheng, Björn Berglund, Cecilia Stålsby Lundborg, Stefan Börjesson, Xuewen Li, Baoli Chen, Hong Yin,

Antimicrobial Agents and Chemotherapy · 2017 · 63 citations · 11 references

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Concepts

Abstract

ABSTRACT We report on the coexistence of mcr-1 and bla CTX-M in multidrug-resistant, extended-spectrum β-lactamase-producing Escherichia coli belonging to the sequence type 10 complex isolated from well water in rural China. Raoultella ornithinolytica with bla KPC-2 was also detected in well water from the same area. This study shows that genes coding for resistance to last-resort antibiotics are present in wells in rural China, indicating a potential source of antibiotic resistance.

References

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<i>bla</i> <sub>CTX-M</sub> Genes in Clinical <i>Salmonella</i> Isolates Recovered from Humans in England and Wales from 1992 to 2003

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Nationwide high prevalence of CTX-M and an increase of CTX-M-55 in Escherichia coli isolated from patients with community-onset infections in Chinese county hospitals

Jing Zhang, Beiwen Zheng, Lina Zhao et al. · BMC Infectious Diseases · 2014 · 165 citations · Full text

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High prevalence of blaCTX-M extended-spectrum β-lactamase genes in Escherichia coli isolates from pets and emergence of CTX-M-64 in China

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